Contact Information

John H. Schild, PhD
Associate Professor
Department of Biomedical Engineering
IUPUI Room SL 220
723 West Michigan Street
Indianapolis, IN 46202
Phone: 317-274-9747
Fax: 317-278-2032
email: jschild[@]iupui[dot]edu

 "It is part of the general pattern of misguided policy that our country is now geared to an arms economy which was bred in an artificially induced psychosis of war hysteria and nurtured upon an incessant propaganda of fear."

General Douglas MacArthur,  Speech, May 15, 1951

Teaching | Education | Research | Publications 

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Education


Ph.D., Electrical Engineering, Rice University, 1994
M.S., Biomedical Engineering, Case Western Reserve University, 1988
B.S., Biomedical Engineering, Case Western Reserve University, 1983 

 

Research Interests 

Computational neuroscience
Sensory neuron and synapse electrophysiology
Neural coding in cardiovascular afferents
Patch clamp instrumentation
 

Recent Academic Responsibilities 

  • BME 602 Principles of Biomedical Engineering II
  • BME 595 Biosignals and Systems
  • BME 595 Bioelectric Phenomena
  • BME 595 Experimental Methods for Biomedical Engineers
  • BME 595 Sensors and Implantable Devices
  • BME 331 Biosignals and Systems
  • CSCI 595 Computational Neuroscience
  • ECE 302 Probabilistic Methods in Electrical Engineering
  • ENGR 196 Engineering Problem Solving
  • PSY 615 Behavioral Neuroscience (guest lectures)
  • BIOL 556 Physiology I (guest lectures)
  • BME595A : origin and control of transmembrane voltage and current – 1cr.
  • BME595B : quantitative analysis of whole-cell and single channel ionic currents – 1 cr.
  • BME595C : origin and analysis of extracellular biopotentials – 1 cr.

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Research Funding 

 

Fellowships 

 

Selected Publications  

·         Wladyka CL, Feng B, Glazebrook PA, Schild JH, Kunze DL. The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats. J Physiol. 2008 Feb 1;586(3):795-802

·         Feng B, Li BY, Nauman EA, Schild JH. Theoretical and electrophysiological evidence for axial loading about aortic baroreceptor nerve terminals in rat. Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3659-72

·         Li BY, Feng B, Tsu HY, Schild JH. Unmyelinated visceral afferents exhibit frequency dependent action potential broadening while myelinated visceral afferents do not. Neurosci Lett. 2007 Jun 21;421(1):62-6.

·         Li BY, Schild JH. Electrophysiological and pharmacological validation of vagal afferent fiber type of neurons enzymatically isolated from rat nodose ganglia. J Neurosci Methods. 2007 Aug 15;164(1):75-85.

·         Li B, Schild JH. Persistent tetrodotoxin-resistant Na+ currents are activated by prostaglandin E2 via cyclic AMP-dependent pathway in C-type nodose neurons of adult rats. Biochem Biophys Res Commun. 2007 Apr 20;355(4):1064-8.

·         Y.H. Jin, T.W. Bailey, B.Y. Li, J.H. Schild, M.C. Andresen. P2X and VR1 receptor activation releases glutamate from separate cranial afferent terminals in nucleus tractus solitarius. Journal of Neuroscience, Vol. 24(20), 4709-4717, 2004

·         Y.H. Jin, T.W. Bailey,M.W. Doyle, B.Y. Li, S.K. Chang, J.H. Schild, D. Mendelowitz, M.C. Andresen. Ketamine differentially blocks sensory afferent synaptic transmission in medial nucleus tractus solitarius (mNTS). Anesthesiology, Vol. 98(1), 121-32., 2003

·         P.A. Glazebrook, A.N. Ramirez, J.H. Schild, C.C. Shieh, T. Doan, B.A. Wible, D.L. Kunze. Potassium channels Kv1.1, Kv1.2 and Kv1.6 influence excitability of rat visceral sensory neurons. Journal of Physiology, Vol. 541, 467-482, 2002

·         B.Y. Li and J.H. Schild. Patch clamp electrophysiology in nodose ganglia of adult rat. Journal of Neuroscience Methods, Vol. 115(2), 157-67, 2002

·         W. Fan, J.H. Schild and M.C. Andresen. Graded and dynamic reflex summation of myelinated and unmyelinated rat aortic baroreceptors. American Journal of Physiology, Vol. 277, R748-R756, 1999

·         J.H. Schild and D.L. Kunze. An experimental and modeling study of Na+ current heterogeneity in rat nodose neurons and its impact on neuronal discharge. Journal of Neurophysiology, Vol. 78:3198-3209, Dec. 1997

·         J.H. Schild, J.W. Clark, C.C. Canavier, D.L. Kunze and M.C. Andresen. Afferent synaptic drive of rat medial nucleus tractus solitarius neurons: Dynamic simulation of graded vesicular mobilization, release and non-NMDA receptor kinetics. Journal of Neurophysiology, Vol. 74(4):1529-1547, Oct. 1995.

·         J.H. Schild, J.W. Clark, H. Hay, D. Mendelowitz, M.C. Andresen and D.L. Kunze. A- and C-type rat nodose sensory neurons: Model interpretations of dynamic discharge characteristics. Journal of Neurophysiology, Vol. 71: 2338-2358, 1994.

·         J.H. Schild, S. Khushalani, J.W. Clark, D.L. Kunze, M.C. Andresen and M. Yang. An ionic current model for neurons in the rat medial nucleus tractus solitarius receiving sensory afferent input. Journal of Physiology, Vol. 469: 341 - 363, 1993. 

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Professional Societies 

 

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Miscellaneous information

This is just a random list of links and archive of materials that
I have found interesting. Some are resources that were difficult
to locate at the time I needed the information. While others are
nothing more than a blog of what I happen to be reading that day
and for whatever reason wanted to share w/you. peace, jhs.
(updated 05/16/06)

Ø      Funding miscellanea:
NIH Releases Medical School Funding Data - FY2004
The new and improved NRSA from NIH
 

Ø      Important information from the American Heart Association regarding cardiovascular disease in the USA.
 

Ø      The Accreditation Board for Engineering and Technology has established criteria for accrediting engineering programs.

Ø      Who would have thought Hubert Humphrey would have had it so right way back in 1972?
 

Ø      If you ever wanted the skinny on the Test of English as a Foreign Language (TOEFL) this site will help
 

Ø      The Virtual Hospital (lack of funding hits the sciences again!)
This is a digital library of health information I found this site one morning while looking for neuroanatomical slides and absolutely NOTHING got done the rest of the day. Kudos to the University of Iowa for setting this up. My favorites are the Anatomy and Cell Biology textbooks and in particular the electronic brain atlas
 

Ø      Image from ISAT of the US @ night during the grid failures on 8/14/2003.
A full report is available. If you are at all interested in how the power grid works here in North America, it is worth the read.

Ø      Normative physiological values for the generic laboratory rat

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